scholarly journals The role of radiation therapy in the management of metastatic renal cell carcinoma

Cancer ◽  
1983 ◽  
Vol 51 (4) ◽  
pp. 614-617 ◽  
Author(s):  
Edward C. Halperin ◽  
Leon Harisiadis
2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
An Uche ◽  
Chad Sila ◽  
Tad Tanoura ◽  
James Yeh ◽  
Neil Bhowmick ◽  
...  

Cabozantinib represents an established vascular endothelial growth factor- (VEGF-) tyrosine kinase inhibitor (TKI) in the treatment paradigm of metastatic renal cell carcinoma (mRCC). Its activity in mRCC patients with brain metastases (BMs) has been largely underreported in prospective clinical trials. We present the unique case of a heavily pretreated mRCC patient with BMs who achieved a brain complete response to cabozantinib prior to receiving radiation therapy. We end with a literature review and discussion of the biologic rationale and growing evidence supporting the intracranial activity of cabozantinib.


2021 ◽  
Vol 47 (Supp1) ◽  
pp. S79-S84
Author(s):  
Charles Van Praet ◽  
◽  
Charlotte Slots ◽  
Nikhil Vasdev ◽  
Sylvie Rottey ◽  
...  

2013 ◽  
Vol 62 (12) ◽  
pp. 1757-1768 ◽  
Author(s):  
Matteo Santoni ◽  
Francesco Massari ◽  
Consuelo Amantini ◽  
Massimo Nabissi ◽  
Francesca Maines ◽  
...  

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